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are there any known issues with the actual patchlevel of ESXi - or can I install all updates?
What do you mean by all updates?, all ESXi updates?
We explain all over our website why you should never be among the first to try anything in life. By doing so you are becoming the explorer on thin ice, this is especially obvious for production systems.
Nonetheless we can't prevent people from doing whatever they want, or from testing new releases, which on its own is not a bad thing to do, so XSIBackup has been tested in ESXi 6.7.0 Update 2 and is behaving O.K. so far. It's quite stable, so we don't think any important bug will be found. In regards to newer updates than Update 2... they should be minor updates, but we are used to see almost anything, so be careful.